When Mr and Mrs Little (Hugh Laurie and Geena Davis) visit an orphanage to find a brother for their son George (Jonathan Lipnicki) they come away with a charming talking mouse called Stuart. After initial misgivings, George and Stuart begin to get on famously, and everything seems to be going perfectly; but unknown to the family, the neighbourhood cats have ganged together with the sole intention of getting rid of Stuart. Co-written by M. Night Shyamalan ('The Sixth Sense') and featuring state-of-the-art computer-generated effects and Michael J. Fox as the voice of Stuart.

This adult sex comedy cartoon is an updated version of Tarzan, with the Lord of the Jungle completely dominated by a strident Jane. With the voices of Johnny Weissmuller Jr, John Belushi and Bill Murray.